Article Details


B Imhof & G McFeat.
Handbook of Cosmetic Science and Technology, 4th Edition (Editors: AO Barel, M Paye & HI Maibach), 11, 131–140, CRC Press 2014.
Print ISBN: 978-1-84214-564-7, eBook ISBN: 978-1-84214-565-4.



The importance of TEWL as a measure of the skin barrier is well recognised and instruments are now available for the rapid and reliable evaluation of skin barrier function. The open-chamber method is well established and has been used extensively in recent years despite its vulnerability to external air movements. The new generation of closed-chamber instruments extend application away from highly controlled laboratory environments with portability a key feature of the VapoMeter and accuracy a major strength of the AquaFlux™. However, results observed with any instrument are only meaningful if potentially confounding variables are recognised, controlled or otherwise allowed for. Under these conditions, TEWL measurement is undoubtedly an excellent method for the evaluation of skin barrier function.


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