Pioneering Developer of research-grade TEWL + Skin Hydration Measurement Devices


AquaFlux™ condenser-chamber TEWL measurement device uses a unique patented technology that eliminates weaknesses associated with other open and closed chamber TEWL measurement devices, providing users with unrivalled application flexibility, sensitivity and accuracy.

Epsilon™ skin hydration measurement device, uses a calibrated capacitance contact imaging system with exceptional analysis capabilities for moisture content, perspiration, membrane integrity, wrinkles & skin topology (micro-relief).

For over two decades, customers worldwide have been using our patented technology to provide faster, more accurate characterisations of bio-tissues such as skin, hair & nails, and their interactions with cosmetic, pharmaceutical & medical products.

TEWL + Skin Hydration Instruments AF200 and E100
TEWL + Skin Hydration Instruments AF200 and E100

Our Products

Patented TEWL Measurement Device
AquaFlux TEWL Measurement System
AquaFlux TEWL Measurement System

AquaFlux™ Model AF200 Evaporimeter

The AquaFlux™ is an evaporimeter for TEWL measurement with a unique patented technology that overcomes challenges of both open and closed-chamber methods with a condenser that continuously removes water vapour by converting it to ice. AquaFlux™ out-performs all its competitors in terms of accuracy, sensitivity, repeatability, reproducibility and versatility (supported by numerous studies available). More …


  • Fast, non-stop TEWL measurement
  • Best accuracy, sensitivity, repeatability
  • Any site, any angle, anywhere
  • Versatile: in-vivo, in-vitro, skin, scalp, lips, nail, …
  • Membrane integrity & 3D skin culture testing
  • Traceable calibration, independently verified
  • Free software updates

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Epsilon Skin Hydration Measurement Systems
Epsilon Skin Hydration Measurement Systems

Epsilon™ Model E100 Contact Imaging System

The Epsilon™ integrated technology provides both image and hydration data simultaneously (suitable for both In-vivo + In-vitro measurements). It differs from similar devices in its linear and calibrated response, where every pixel in the image provides a reproducible measurement that can be interpreted in terms of hydration. Equipped with 76800 sensors the Epsilon™ can measure SC hydration with greater accuracy and flexibility than conventional single-sensor probes. More …


  • Capacitance measurement principle
  • Linear & calibrated response
  • In-vivo & in-vitro, static & dynamic measurements
  • Hydration measurement on skin, hair, …
  • Micro-relief characterisation
  • 50µm image resolution, <5µm sensing depth
  • Sensing area 12.8 x 15mm
  • Free software updates

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Pixience C-Cube Dermoscope
Pixience C-Cube Dermoscope

Pixience C-Cube Dermoscope

The C-Cube Dermoscope from Pixience SA, France, is the fastest way of analysing the skin. Its unprecendented metric and colour standardisation of images allows you to asess more than 20 useful criteria from a single image. Biox is the exclusive distributor of this system in the UK and Irish Republic. More …


  • Ultra-high definition 3664×2748 pixel images
  • Glare-free images, 50x magnification
  • Automatic camera settings for reliable measurements
  • Analysis of skin micro-relief & texture via 3D reconstruction
  • Analysis of pores, seborrhea, redness & vascularisation
  • Analysis of pigmentation, age spots, & make-up
  • Analysis of dryness & desquamation
  • Software with protocol management for clinical research
  • Expert image analysis options via Cloud
  • In-vitro accesories for liquids, powders, creams, etc

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Our Services

Consultancy Services

We can offer a range of consultancy services associated with the instruments we manufacture, as listed below. Please note, however, that we do not do clinical trials. More…


  • Feasibility Trials
  • Training
  • Custom Design & Fabrication
  • Software Adaptation
  • Workshops

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