Pioneering Manufacturers of research-grade TEWL + Skin Hydration Measurement Devices

Our products, the AquaFlux™ evaporimeter and the Epsilon™ contact imaging system measure quantities such as TEWL, SSWL, hydration, perspiration, membrane integrity, wrinkles & skin topology (micro-relief).

Biox systems Ltd was established in the year 2000, with a mission to offer a unique technology that eliminates standard weaknesses of both open and closed chamber TEWL measurement devices. Over two decades later, customers worldwide are using our patented technology to provide faster & more accurate characterisations of bio-tissues such as skin, hair & nails, and their interactions with cosmetic, pharmaceutical & medical products.

TEWL + Skin Hydration Instruments AF200 and E100

Our Products

Patented TEWL Measurement Device

AquaFlux TEWL Measurement System

AquaFlux™ Model AF200 Evaporimeter

The AquaFlux™ is an evaporimeter for TEWL measurement with a unique patented technology that overcomes challenges of both open and closed-chamber methods with a condenser that continuously removes water vapour by converting it to ice. AquaFlux™ out-performs all its competitors in terms of accuracy, sensitivity, repeatability, reproducibility and versatility (supported by numerous studies available). More …

Fast, non-stop TEWL measurement
Best accuracy, sensitivity, repeatability
Any site, any angle, anywhere
Versatile: in-vivo, in-vitro, skin, scalp, lips, nail, …
Membrane integrity & 3D skin culture testing
Traceable calibration, independently verified
Free software updates

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Epsilon Skin Hydration Measurement Systems

Epsilon™ Model E100 Contact Imaging System

The Epsilon™ integrated technology provides both image and hydration data simultaneously (suitable for both In-vivo + In-vitro measurements). It differs from similar devices in its linear and calibrated response, where every pixel in the image provides a reproducible measurement that can be interpreted in terms of hydration. Equipped with 76800 sensors the Epsilon™ can measure SC hydration with greater accuracy and flexibility than conventional single-sensor probes. More …

Capacitance measurement principle
Linear & calibrated response
In-vivo & in-vitro, static & dynamic measurements
Hydration measurement on skin, hair, …
Micro-relief characterisation
50µm image resolution, <5µm sensing depth
Sensing area 12.8 x 15mm
Free software updates

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Pixience C-Cube Dermoscope

The C-Cube Dermoscope from Pixience SA, France, is the fastest way of analysing the skin. Its unprecendented metric and colour standardisation of images allows you to asess more than 20 useful criteria from a single image. Biox is the exclusive distributor of this system in the UK and Irish Republic. More …

Ultra-high definition 3664×2748 pixel images
Glare-free images, 50x magnification
Automatic camera settings for reliable measurements
Analysis of skin micro-relief & texture via 3D reconstruction
Analysis of pores, seborrhea, redness & vascularisation
Analysis of pigmentation, age spots, & make-up
Analysis of dryness & desquamation
Software with protocol management for clinical research
Expert image analysis options via Cloud
In-vitro accesories for liquids, powders, creams, etc

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Our Services

Consultancy Services

We can offer a range of consultancy services associated with the instruments we manufacture, as listed below. Please note, however, that we do not do clinical trials. More…

Feasibility Trials
Training
Custom Design & Fabrication
Software Adaptation
Workshops

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