Cosmetic, Pharmaceutical & Related Industries

ACT Co Ltd, S Korea
Amore Pacific, S Korea
Ands Corporation, Japan
Ashland Specialty Ingredients, France
Beiersdorf AG, Germany
Boehringer Ingelheim Pharmaceuticals, USA
Boots the Chemist, UK
Cognis GmbH, Germany
Colgate Palmolive, USA
Cosmax, S Korea
Cosmos Technical Center Co Ltd, Japan
CNP Cosmetics Co., Ltd, S Korea
Croda Europe, UK
Croda Inc, USA
Croda Singapore Pte Ltd, Singapore
Deb Group Ltd, UK
Dermal Laboratories Ltd, UK
Dezhou Onlystar Biotechnology Co., Ltd, PR China
DSM Nutritional Products Ltd, Switzerland
Dow Corning Europe SA, Belgium
Dow Pharmaceutical Sciences, Inc, USA
Estée Lauder Companies, USA
Estée Lauder Coordination Center BVBA, Belgium
Expanscience Laboratories, France
Fancl Corporation, Japan
Firmenich SA, Switzerland
Galderma R&D, France
gCt-cosmetic GmbH, Germany
ghd Ltd, UK
Gillette Advanced Technology Centre, UK
Gillette, USA
GOJO Industries Inc, USA
GSK Stiefel, USA
Guangzhou Marubi Biotechnology Co Ltd, PR China
Henkel AG & Co. KGaA, Germany
Hexal AG, Germany
HPRD – Health Products Research and development Lda, Portugal
Institut de Recherche Pierre Fabre, France
Laboratoires Innothera, France
Instituto de Fotomedicina, Spain
ISP Corporation, USA
ITC Ltd, India
Jahwa United Company Ltd, PR China
Johnson & Johnson, France
Johnson & Johnson, USA
Ju Zheng (Shanghai) Biotechnology Co Ltd, PR China
Kao Corporation, Japan
Kao Corporation, USA
Kern Pharma, Spain
Kimberly-Clark Corp, USA
L’Oréal, India
L’Oréal Recherche, France
L’Oréal, USA
Laboratoire Clarins, France
LTS Lohmann Therapie-Systeme AG, Germany
Mandon Corporation, Japan
Medi Kinetics Co Ltd, South Korea
MedPharm R&D Centre, UK
Miura Co Ltd, Japan
Mylan Pharmaceuticals, USA
Natural Solution Co Ltd, S Korea
Nihon Kolmar Co Ltd, Japan
Novartis, USA
Novartis Consumer Health SA, Switzerland
Nutri-Woods Holdings Corporation, PR China
Oriflame Cosmetics AB, Sweden
Oriflame Global Technical Center, Ireland
P&G Braun GmbH, Germany
Pantec Biosolutions AG, Liechtenstein
Pechoin, PR China
Pentapharm, Switzerland
Permamed AG, Switzerland
Pfizer, USA
Philips Research, The Netherlands
Philips Research Asia, PR China
Phosphagenics Ltd, Australia
Procter & Gamble, Belgium
Procter & Gamble, PR China
Procter & Gamble, Singapore
Procter & Gamble, UK
Procter & Gamble, USA
PZ Cussons Ltd, UK
Riemann A/S, Denmark
Samyang Holdings, S Korea
SCA Hygiene Products AB, Sweden
Scibeauty Solutions, PR China
Sederma, France
Shanghai Jahwa United Company Ltd, PR China
Shiseido Research Center, Japan
Sunstar Inc, Japan
Taro Pharmaceuticals, Canada
The Lubrizol Corporation, USA (Speciality Chemicals)
TransForm Pharmaceuticals, USA
Unilever Japan KK, Japan
Unilever R&D Colworth, UK
Unilever R&D Port Sunlight, UK
Unilever R&D Trumble, USA
Unilever R&D Shanghai, PR China
Unilever Thai Holding Ltd, Thailand

Contract Research Organisations

Alba Science Ltd, UK
Ameriderm Research, USA
BioScreen Testing Services, Inc. USA
bioskin GmbH, Germany
Center for Clinical Studies, USA
CERCO, France
Charles River Laboratories, UK
Clinical Research Center of Alabama, USA
Coastal Clinical Research, Inc, USA
Consumer Product Testing Company Inc, USA
Coty Testing Institute, USA
Cutest Systems Ltd, UK
Derma Consult GmbH, Germany
Dermapro Co, Ltd, Korea
Dermatest GmbH, Germany
Dermatology Research Associates, USA
Derm Research @ 888 Inc, Canada
Ellead Skin & Bio Research, S Korea
Eviderm Institute AB, Sweden
Gunsynd plc, UK
Intertek Clinical Research Services, UK
Intertek Services Etudes Cliniques, France
Innovaderm Research, Canada
Jacksonville Center for Clinical Research, USA
KC Clinical Skin Research Center Co. Ltd, S Korea
Laboratoire Dermscan, France
Laboratoire Dermscan, Poland
Medi Kinetics Co Ltd, S Korea
Ora, Inc, USA
ORIX Rentec Corporation, S Korea
Probity Medical Research Inc, Canada
proDERM Institut für Angewandte Dermatologische Forschung GmbH, Germany
Progressive Clinical Research, USA
Radiant Research, Inc, USA
Rocky Mountain Biosystems Inc, USA
SIT Skin Investigation and Technology GmbH, Germany
Skin Search of Rochester, Inc, USA
SPRIM, Thailand
Stephens & Associates Inc, USA
Tennessee Clinical Research Center, USA
Welland Medical Limited, UK
XLR8 Medical Research, Inc, Canada

Hospital, Medical School & University Research

Ann & Robert H Lurie Children’s Hospital of Chicago, USA
Anam University Hospital, Allergy Clinic, S Korea
Alexandria University, Egypt
Arizona State University, USA
Beijing Institute of Traditional Chinese Medicine, PR China
Brunel University, UK
Charles University in Prague, Czech Republic
Children’s Medical Center, USA
Chinese Center for Disease Control and Prevention, PR China
College of Pharmacy & Pharmaceutical Sciences, Frederic and Mary Wolfe Center, USA
Curtin University, Australia
Dankook University Medical College, S Korea
El Camino Hospital, Canada
Fairleigh Dickinson University, USA
Federal University of Pernambuco, Brasil
First Hospital of China Medical University, PR China
Gentofte Hospital, Denmark
Glostrup University Hospital, Denmark
Hallym Polytechnic University, Rehabilitation Therapy Department, S Korea
Harvey Mudd College, USA
Herlev Hospital, Denmark
Inha University Hospital, S Korea
Jeju National University Hospital, S Korea
King Faisal University, College of Clinical Pharmacy, Saudi Arabia
KonKuk University, S Korea
Korea Institute for Skin and Clinical Sciences, S Korea
Korea University Anam Hospital, S Korea
Linköping University Hospital, Sweden
London School of Pharmacy, UK
London College of Fashion, UK
Long Island University, Department of Pharmaceutical Sciences, USA
Liverpool Women’s Hospital, UK
Massachusetts General Hospital (CURTIS), USA
MedStar Harbor Hospital, USA
Monash University, Australia
Mt Sinai Medical Center, USA
National Jewish Medical Center, USA
Ninewells Hospital and Medical School, University of Dundee, Scotland
NorthShore University HealthSystem, USA
Northwestern University, Department of Dermatology, USA
Oregon Health & Science University, USA
Qilu University of Technology, PR China
Radboud University Medical Center, The Netherlands
Rady Children’s Hospital, USA
Rutgers University, USA
Santa Monica Clinical Science Institute, USA
Sefako Makgatho Health Sciences University, South Africa
Semyung University, Clinical Trial Center for Bio-Industry, S Korea
Shanghai Institute of Technology, PR China
Shanghai Skin Disease Hospital, PR China
Siriraj Hospital at Mahidol University, Thailand
Skokie Hospital, NorthShore University HealthSystem, USA
St Thomas’ Hospital, UK
St Vincent’s Hospital of Catholic University, S Korea
Technische Universität München, Department of Dermatology and Allergy, Germany
Telethon Kids Institute, Australia
TU Delft, The Netherlands
UCSD School of Medicine, Department of Dermatology, USA
Universität des Saarlandes, Helmholtz-Institut, Germany
Universität Hamburg, Germany
Universität Heidelberg, Medizinische Fakultät Mannheim, Germany
Universität Wien, Austria
Universitätsklinikum Schleswig-Holstein, Germany
Université de Lyon, France
Universiteit Leiden, The Netherlands
University Anam Hospital, S Korea
University College London, UK
University of Alabama at Birmingham, USA
University of Bath, UK
University of California, San Francisco, USA
University of Central Lancashire, UK
University of Colorado, School of Mines, USA
University of Florida, College of Medicine, USA
University of Hertfordshire, UK
University of Keele, UK
University of Leeds, UK
University of Limpopo, South Africa
University of Manchester School of Nursing Midwifery and Social Work, UK
University of Pittsburgh, USA
University of Queensland, Australia
University of Rochester Medical Center, USA
University of Sheffield School of Medicine & Biomedical Sciences, UK
University of South Alabama Children’s and Women’s Hospital, USA
University of South Australia, Australia
University of Strathclyde, UK
University of Texas, Southwestern Medical Center, USA
University of the Arts, UK
University of Western Australia, Princess Margaret Hospital for Children, Australia
VetAgro Sup, France
Vrije Universiteit Brussel, Belgium
Wake Forest Baptist Medical Center, USA
Wake Forest University, USA
West China Hospital, Sichuan University, PR China
Wonkwang University, Oriental Medicine Hospital, S Korea

Medical, Health & Pharmaceutical Research Organisations

Alcare Co., Ltd, Japan
Bakersfield Dermatology & Skin Cancer Medical Group, USA
CHDR Centre for Human Drug Research, The Netherlands
Clinical Partners, Johnston, USA
Concept Life Sciences, UK
Institute of Natural Cosmetic Industry, S Korea
Jacksonville Center for Clinical Research, USA
Joanneum Research, Forschungsgesellschaft mbH, Austria
Korea Institute for Skin and Clinical Sciences, S Korea
Hamzavi Dermatology of Fort Gratiot, USA
Health Protection Agency (HPA), UK
Helmholtz Zentrum München, Germany
Institute of Molecular and Cell Biology, Singapore
Institute of Natural Cosmetic Industry, S Korea
Malaghan Institute of Medical Research, New Zealand
National Institute for Occupational Safety and Health (NIOSH), USA
Oregon Medical Research Center, USA
Renstar Medical Research, USA

Other Industries & Organisations

Bundesinstitut für Risikobewertung, Germany
Centre de Recherches du service de santé des armées (CRSSA), France
Institut Français du Textile et de l’Habillement (IFTH), France
Nano and Advanced Materials Institute Limited, Hong Kong
National Physical Laboratory (NPL), UK
Shanghai Tian Mei Information Technology Co Ltd, PR China
Syngenta Ltd, UK

AquaFlux™ User Feedback

Click to open the AquaFlux™ User Feedback


We routinely use our 3 Aquaflux™ probes in clinical trials which perform well with reliable data.
Dr. David Black, Skin Research Centre, Pierre Fabre Dermocosmétique, France.


It is my pleasure to recommend the Aquaflux™. As a device we have found it to be durable, that it is easy to calibrate and use and measures quickly. The measurements are highly repeatable with little variation between users. Biox has provided great service. Before the sale they took the time and effort to understand our particular needs (measurement in critically ill premature neonates). The personal training got us up to speed in short order. Since our purchase, Biox has engineered a USB solution for our parallel adapter device that has allowed us to use newer computers with our older Aquaflux™. Our questions have always been answered promptly and completely, although we have had little need for support.
Dr. Charles R Hamm, Jr. University of South Alabama Children’s and Women’s Hospital, USA.


We have two AquaFlux™ devices in the laboratory and they are used by everyone in the group. We find them reliable, robust and accurate, providing data in which we have full confidence. Technical support from the manufacturer is exemplary.
Prof. Richard H. Guy, Department of Pharmacy & Pharmacology, University of Bath. UK.


Aquaflux™ is an easy-to-use device. The closed chamber allows more relevant and reproducible measurements of TEWL than other devices. We enjoy very much to use it and to work with Biox team, always ready to cross Europe to help us!
Anne Viola, Laboratoire Dermscan, France.


The Aquaflux™ is an excellent instrument that has performed robustly even in our three month old baby study. The BIOX Team is always available to answer questions down the line, and I can highly recommend it for both clinical and research use.
Dr Carsten Flohr, National Institute for Health Research, UK.


A versatile instrument, reliable for many in vivo and in vitro measurements with reproducible data, easy to manipulate, broader applications in personal care, pharma, dermatological research. The software is well written, user friendly, and the manual is easy to read and follow. Well done to the Biox team!!!!
Mihaela Gorcea, International Specialty Products, USA.


Time and again our Aquaflux™ has performed well in our clinical studies. The ability to see and analyse the water coming from the skin in real time gives it a distinct advantage over conventional ‘single digit’ devices.
Dr Jonathan Crowther, Procter and Gamble, UK.


The Aquaflux™ is highly pratical for measuring the TEWL. We are using it in vivo and in vitro. The data are reproducible and the customer support is excellent.
Prof. Claudia Valenta, University of Vienna, Austria.


New user in 2008 I was very pleased to have invaluable help and good support from Biox team to use Aquaflux™ to its best avantage. Today researchers and technicians of our lab are agree to say that AquaFlux™ is a good equipment, easy to use, with reproducible data.(We use this device in wound healing studies).
Cécile Cléry-Barraud,PhD. IRBA, La Tronche, France.


We are getting on quite well with the AquaFlux™ indeed! we are exploring with this equipment the quantification and early detetction of malfunctioning of sudomotor neurons in patients suffering e.g. diabetic neuropathy, CRPS, small fibre neuropathy, critical illness etc and thereby may contribute a new diagnostic clinical tool.
Dr Roman Ruckwied, Department of Anaesthesiology and Intensive Care Medicine, University of Heidelberg, Germany.


The AquaFlux™ is a very good device and the staff of Biox is very competent and nice.
Marc Crozet, Essor Technologies, France.


I’m very happy with the AqaFlux, it’s easy to operate the machine and the manual is very readily comprehensible written.
LTS Lohmann Therapie-Systeme AG, Germany.


I have been investigating the biophysical properties of the skin since the early 70s. Over the years the technology to probe the nature of the stratum corneum has advanced significantly and one determinant that is particularly important is the transepidermal water loss. Various approaches have been made to accomplish this but my research team finds that the Aquaflux™ proves a simple, reliable and robust method for monitoring TEWL. It does not suffer the vagaries of open chamber equipment and the various parameters that can be obtained from the data that the Aquaflux™ provides give very good indicators of the water flux through the skin and the capacity of the skin for water. Its sophistication has allowed us to conduct a detailed analysis of the variation of TEWL with body site and relate this to the diffusional pathlength of water through the stratum corneum. Any laboratory interested in the barrier properties of the skin should evaluate this technology for its ease of use and reliability.
Prof Jon Hadgraft, London School of Pharmacy, UK.


In our institute we are using the Aquaflux™ in an unusual application to evaluate the water behavior of fabrics and textiles components. This device gives accurate and reliable measurements. Its use is very simple and the staff is very competent.
Dr Olivier Raphaël, R&D Projects manager, IFTH, France.


The measuring capacity of the Aquaflux™ allows us to use the instrument in exercise physiology in the evaluation of sweat rates. The instrument is easy in use, no discomfort for the athletes and real time results.
Professor Peter Clarys, Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Belgium.


The AquaFlux is a user friendly instrument that provides more accurate and reproducible measurements compared to open chamber TEWL measuring instruments. Ideal for assessing skin barrier function and water loss for in-vivo clinical studies.
Michelle Walsh, Oriflame R&D Ltd, Ireland.